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--- url: https://avea-life.com/products/sereniser title: Unknown scraped_at: 2025-11-29 type: shopify --- 4.8/5 based on over 800 ratings ### Our review platforms Overall **4.8** based on **921** reviews Powered by Top rated on the independent review platform [Trustpilot](https://www.trustpilot.com/review/avea-life.com "https://www.trustpilot.com/review/avea-life.com") ### Sereniser The Sereniser is your non-hormonal solution to truly restorative sleep – helping you fall asleep faster, stay asleep longer, and wake up clear-headed and energised. Its clinically studied ingredients calm the mind, promote deeper, uninterrupted sleep, and regulate natural sleep cycles, ensuring you wake up recharged and ready for the day. - Fall asleep faster – feeling calm and relaxed - Sleep deeper for longer – with uninterrupted, restorative rest - Wake up refreshed – thanks to optimised sleep quality - Start your day clear and energised – with no grogginess or fog [Shop Now](https://avea-life.com/products/sereniser#scroll-to-pdp-div) Manufactured in Switzerland Based on cutting-edge research Try without risk 90 days money back guarantee Support deep, restorative sleep – naturally. Unlike most sleep supplements that rely on melatonin or sedatives to force sleep, we intentionally designed our Sereniser to support your body’s natural sleep-wake cycle. Developed with longevity researchers in Switzerland, it takes a multi-pathway approach grounded in neuroscience and chronobiology to support mood, cortisol balance, circadian rhythm, and deep sleep architecture – all without disrupting your body’s natural rhythms. Fall Asleep FasterCircadian Rhythm Regulation This targeted blend of plant-based extracts – including Green Tea, Saffron, and Holy Basil – works in synergy to calm the mind and body. L-Theanine from green tea extract promotes a relaxed, focused state without drowsiness. Holixer® (from Holy Basil) has been clinically shown to lower cortisol levels, easing the transition into sleep¹. Safr’Inside™, a patented saffron extract, enhances sleep quality and reduces mental stress². Holixer® helps regulate cortisol levels, while Safr’Inside™ improves sleep quality and reduces stress. Together, they naturally support the body’s circadian rhythm and the natural melatonin production. Magnesium and Vitamin B6 support GABA activity – helping you fall asleep and wake in better alignment with your body’s natural rhythm – without external melatonin. - Fall Asleep Faster This targeted blend of plant-based extracts – including Green Tea, Saffron, and Holy Basil – works in synergy to calm the mind and body. L-Theanine from green tea extract promotes a relaxed, focused state without drowsiness. Holixer® (from Holy Basil) has been clinically shown to lower cortisol levels, easing the transition into sleep¹. Safr’Inside™, a patented saffron extract, enhances sleep quality and reduces mental stress². - Circadian Rhythm Regulation Holixer® helps regulate cortisol levels, while Safr’Inside™ improves sleep quality and reduces stress. Together, they naturally support the body’s circadian rhythm and the natural melatonin production. Magnesium and Vitamin B6 support GABA activity – helping you fall asleep and wake in better alignment with your body’s natural rhythm – without external melatonin. - Deeper Sleep Support Sereniser combines Serezin™, Magnesium Glycinate, and Vitamin B6 + Safr’Inside™ to support all phases of sleep – from onset to deep rest. Serezin™ helps reduce nighttime discomfort, Magnesium Glycinate relaxes muscles and nerves, while B6 and Safr’Inside™ promote natural melatonin production – supporting deeper, more restorative sleep and improved next-day focus. - Refreshed Mornings Unlike sedatives, Sereniser promotes restorative sleep without morning drowsiness or dependency. Serezin™ has been clinically shown to improve sleep quality and morning alertness³ – helping you wake up clear, refreshed, and ready to start the day with focus, energy, and a greater sense of mental and physical well-being. ## The science behind deep, restorative sleep #### Sleep science basics **Sleep is not just about duration – it’s about depth, cycles, and consistency.** Most of us know we need 7–9 hours of sleep, but not all sleep is created equal. Throughout the night, your brain moves through a series of stages—light sleep, deep sleep (also known as slow-wave sleep), and REM sleep (when most dreaming occurs). These stages cycle roughly every 90 minutes and each plays a distinct role in how your body and mind recover. - **Light sleep** helps the body relax and stabilise, preparing for deeper, restorative sleep stages. - **Deep sleep** is when the body repairs muscle, restores energy, and strengthens the immune system. - **REM sleep** supports memory consolidation, emotional processing, and cognitive performance. **But as we age, our sleep architecture begins to shift.** Older adults tend to spend more time in lighter stages and less in slow-wave and REM sleep. The amount of deep sleep for mature adults declines steadily – making sleep more fragmented and less restorative, even if you’re getting enough hours. At the same time, the **circadian rhythm,** your body’s internal clock, becomes less stable. Many people experience a shift known as _phase advance_, feeling sleepy earlier in the evening and waking earlier in the morning, often before they’ve had adequate rest. Hormonal shifts, especially for women during perimenopause and menopause, also contribute to this disruption. These changes don’t just impact how rested you feel – they affect your long-term health. **Deep, uninterrupted sleep is strongly linked to healthy ageing and longevity.** It influences immune resilience, hormone balance, metabolic function, and even how efficiently the brain clears out waste through the glymphatic system. When sleep becomes shallow or inconsistent, the body’s ability to repair, regulate, and renew itself also begins to decline. - Why melatonin and conventional sleep aids may be doing more harm than good To counter these changes, many people turn to over-the-counter melatonin or prescription sedatives (often referred to as _sleeping pills_) or antihistamines. But most of these solutions work by artificially sedating the brain, and may cause more harm than good – particularly as we age. **Melatonin** is a hormone your brain produces in response to darkness. It signals that it’s time to wind down – but it doesn’t control how long you sleep or how deeply you rest. When taken in high doses, at the wrong time, or for extended periods, melatonin can: - Disrupt your body’s natural melatonin production - Disrupt your internal sleep-wake rhythm even further - Cause residual drowsiness, vivid dreams, or headaches over time **Sedatives** go a step further by suppressing brain activity altogether – inducing unconsciousness, but not true sleep. These drugs can interrupt your brain’s natural sleep architecture, preventing you from reaching slow-wave and REM sleep – the very stages responsible for memory consolidation, emotional regulation, and immune function. **Over time, the use of sedatives has also been linked to increased risk of cognitive decline, particularly in older adults.** Instead of forcing sleep, the goal should be to **support** the systems that naturally regulate it – including your circadian rhythm, nervous system, cortisol cycles, and neurotransmitters like GABA and serotonin. This is what allows the body to access real, uninterrupted sleep and with it, the recovery, clarity, and long-term resilience it was designed for. - How does the Sereniser work differently? **A hormone-free, science-backed approach to deeper, more restorative sleep.** Unlike most sleep supplements that rely on melatonin or sedatives to _force_ sleep, we intentionally designed Sereniser to _support_ your body’s _natural_ sleep-wake cycle – without disrupting your hormones, creating dependency, or leaving you drowsy the next day. Formulated with leading longevity researchers in Switzerland, it takes a multi-pathway approach grounded in neuroscience, adaptogens, and chronobiology. Each ingredient was selected for its ability to target key systems involved in high-quality sleep – mood regulation, cortisol balance, circadian rhythm, and sleep architecture – without interfering with your body's natural rhythms. **What makes the Sereniser different:** **1. Calms the body and mind** The Sereniser helps ease the physiological and mental tension that can keep you alert, even when you feel tired. - **L-Theanine** – Promotes calming alpha brain waves to create a relaxed, pre-sleep mental state. - **Holixer® (Holy Basil)** – A clinically studied adaptogen shown to reduce cortisol levels and improve resilience to nighttime stress. - **Safr’Inside™ (Saffron extract)** – Enhances serotonin activity to improve pre-sleep mood, reduce anxiety, and promote natural relaxation. **2. Supports deep, uninterrupted sleep** Rather than simply sedating the brain, Sereniser helps the body reach and maintain deep, restorative sleep stages. - **Serezin™ (Ginger + Frankincense)** – A patented plant-based complex that reduces inflammation-related discomfort and nighttime awakenings. - **Magnesium Bisglycinate** – A gentle, more bioavailable form of magnesium that relaxes muscles and the nervous system to reduce tossing and turning. - **Vitamin B6 + Safr’Inside™** – Together support the natural production of melatonin and GABA, promoting continuous, undisturbed sleep. **3. Balances your internal rhythm** Rather than flooding the system with synthetic melatonin, Sereniser helps regulate your body's own circadian rhythm to promote consistency and better mornings. - **Holixer®** – supports healthy cortisol patterns, helping the body wind down more easily in the evening. - **Safr’Inside™** – enhances serotonin-to-melatonin conversion for smoother transitions into sleep. - **Vitamin B6 & Magnesium** – help reinforce steady sleep patterns by supporting GABA and neurotransmitter balance. **4. Non-habit forming & melatonin-free** Many sleep supplements rely on synthetic melatonin, which can disrupt your natural rhythm and lead to dependency over time. Sereniser takes a more natural, longer-term approach: - No hormonal interference - No tolerance build-up over time - No residual drowsiness or sedation the next day **Just deep, consistent rest - the way your body was designed to experience it.** - Sleep & menopause: What makes women’s sleep different? Women experience sleep differently – and this becomes especially noticeable during perimenopause and menopause. Despite maintaining consistent routines, many begin to experience new or worsening sleep disruptions: difficulty staying asleep, early morning awakenings, or waking feeling less restored than before. These changes are not imagined – they’re physiological. As estrogen and progesterone begin to decline, they also influence the release and amount of other hormones and neurotransmitters that regulate sleep: - **Melatonin**, which governs circadian rhythm - **Cortisol**, which impacts stress and sleep fragmentation - **Serotonin**, which helps calm the nervous system and initiate deep rest When these hormones and neurotransmitters are thrown out of balance, sleep becomes lighter, more fragmented, and more easily disrupted. Hot flashes, increased nighttime cortisol, and changes in thermoregulation all add to the challenge – even for women who’ve never struggled with sleep before. Sleep during menopause is also more sensitive to stress, screen exposure, diet, and even small environmental changes. The nervous system becomes more reactive, and the body may cycle in and out of sleep stages more frequently. But these shifts go beyond night-time rest. Because deep sleep plays a key role in hormone regulation, immune resilience, and cognitive repair, a decline in sleep quality during menopause can also impact **long-term energy, clarity, and healthy ageing**. And yet, most sleep solutions aren’t designed with women in mind — let alone with the complexity of hormonal transitions. Understanding the root causes of disrupted sleep in midlife is essential to supporting better rest – and better health – for decades to come. ## Improve your sleep with the Sereniser and wake up truly rested, fully recharged, and ready to take on the day. ## 93% reported overall better sleep quality\* ## 2× easier to wake up in the morning\* ## 37% experienced reduced stress & cortisol levels after 8 weeks\*\* ## 4 weeks for significantly improved sleep quality\*\*\* \* PLT Health, 2023 (Serezin™ clinical study). \*\* Frontiers in Nutrition, 2022 (Holixer™ clinical trial). \*\*\* Lang et al., medRxiv, 2025 (Safr’Inside™ clinical study). New # Sereniser 60 capsules per bottle        New 4.6/5 (600+ reviews) # Sereniser 60 capsules per bottle $85.00 ~~$0~~Sale _•_ Save The Sereniser features a powerful blend of clinically backed ingredients – including Safr’Inside™, Holixer™, Serezin™, L-theanine, Magnesium Bisglycinate, and Vitamin B6 – that work together to support natural sleep rhythms, balance cortisol, and restore deep, uninterrupted sleep without sedation or habit-forming effects. - Fall asleep effortlessly – with a calm body and clear mind - Sleep through the night – with fewer wake-ups and deeper rest - Reset your sleep rhythm – and wake with steady, lasting energy - Start each day restored – feeling refreshed, focused, and clear-headed Subscribe & Save $49.50$1.65 / serving Save up to 25% Annual Save 25% BEST VALUE Quarterly Save 15% MOST POPULAR Monthly Save 10% 1-month supply delivered monthly Pause or cancel at any time One Time Purchase $55.00$1.83 / serving 1 Unit 3 Units Save 5% 6 Units Save 10% MOST POPULAR 12 Units Save 15% BEST VALUE Add to Cart$49.50 90 days money-back guarantee ### FREE Collagen (€79 value) with every order Receive our best-selling, patented Raspberry Mint Collagen Activator for free with every order this Black Friday, only while stocks last. Daily intake guide Take 2 capsules with water around 1-2 hours before bedtime. If you’re sensitive to supplements, you can start with 1 capsule for a few nights and adjust as needed. * * * Supplement Facts Manufactured in Switzerland Formulated by Experts Sustainable Packaging Clinically proven results Vegan Halal Active ingredients: Green Tea Extract 333mg of which L-Theanine 200mg, Blend of Frankincense and Ginger Extract (Serezin™) 300mg, Holy Basil Extract (Holixer™) 250mg, Magnesium (from Magnesium Bisglycinate) 56.25mg, Saffron Extract (Safr’Inside™) 30mg, Vitamin B6 (Pyridoxal 5-Phosphate) 1.4mg Other ingredients: - Microcrystalline cellulose as bulking agent to ensure the capsule is completely full (active ingredients may not take up enough space), aiding in consistent manufacturing and dosing - Magnesium salts of fatty acids as anti-caking agent to ensure that powdered contents remain free-flowing (important for manufacturing) and to help achieve a consistent mixture of ingredients within the capsule (ensuring proper dosage) - Hydroxypropyl methyl cellulose (HPMC) as glazing agent in form of a vegetable capsule shell * * * Benefit references Our formulations are based on cutting-edge Longevity research. Led by Chief Science Officer Sophie Chabloz, our team collaborates with longevity experts from top institutions to create highly effective, science-backed products. | Ingredients | Benefits | | --- | --- | | Supports a healthy stress response | Promotes healthy sleep quality and duration | Supports healthy melatonin and serotonin balance | Promotes healthy sleep continuity and morning mental clarity | | --- | --- | --- | --- | | Safr’Inside™ (Saffron Extract) | [Pouchieu et al., 2023](https://pubmed.ncbi.nlm.nih.gov/37447245) | [Lian et al., 2022](https://www.sciencedirect.com/science/article/abs/pii/S1389945722000739)<br>[Sadat Rafei et al., 2023](https://pubmed.ncbi.nlm.nih.gov/37484523/) | | [Pachikian et al., 2021](https://pmc.ncbi.nlm.nih.gov/articles/PMC8145009/) | | Holixer™ (Holy Basil Extract) | [Lopresti et al., 2022](https://pubmed.ncbi.nlm.nih.gov/36185698)<br>[Saxena et al., 2011](https://onlinelibrary.wiley.com/doi/10.1155/2012/894509) | | | | | Serezin™ (Ginger + Boswellia Extracts) | | [Salter et al., 2025](https://academic.oup.com/sleep/article/48/Supplement_1/A408/8136199) | | | | L-Theanine (from Green Tea Extract) | [Hidese et al., 2019](https://pmc.ncbi.nlm.nih.gov/articles/PMC6836118/)<br>[Wang et al., 2022](https://www.sciencedirect.com/science/article/pii/S2213453021001324) | [Kim et al., 2019](https://pmc.ncbi.nlm.nih.gov/articles/PMC6366437/) | | | | Magnesium | | [Breus et al., 2024](https://esmed.org/MRA/mra/article/view/5410/99193548123) | [Jadidi et al, 2022](https://pmc.ncbi.nlm.nih.gov/articles/PMC9804944/) | [Abbasi et al., 2012](https://pmc.ncbi.nlm.nih.gov/articles/PMC3703169/) | | Vitamin B6 | | [Lemoine et al, 2019](https://pubmed.ncbi.nlm.nih.gov/31331545/) | [Jadidi et al, 2022](https://pmc.ncbi.nlm.nih.gov/articles/PMC9804944/)<br>[Field et al., 2022](https://pmc.ncbi.nlm.nih.gov/articles/PMC9787829/) | | * * * Sourcing At AVEA, we prioritise transparency and quality. We manufacture in Switzerland and source globally, focusing on ingredients with excellent bioavailability and high activity through standardised plant extracts. Every batch is rigorously double-tested for purity by an independent Swiss lab. We go beyond standard labelling to provide detailed information, and our customer service team is available for any questions or test result requests. | Active ingredients | Supplier | Production method | | --- | --- | --- | | Green Tea Extract with L-Theanine | JiangXi Nanyu Biotechnology Co., Ltd. | Camellia sinensis leaf extraction | | Blend of Frankincense and Ginger Extract (Serezin™) | Laila Nutraceuticals Ltd. | Boswellia serrata gum-resin and Zingiber officinale rhizome extraction | | Holy Basil Extract (Holixer™) | Vivatis Pharma GmbH | Ocimum tenuiflorum leaf extraction | | Magnesium Bisglycinate (Magnesium) | Nutraceuticals Group Europe Ltd. | Chemical synthesis | | Saffron Extract (Safr’Inside™) | ACTIV'INSIDE | Crocus sativus stigma extraction | | Pyridoxal 5-Phosphate (Vitamin B6) | ECSA Chemicals AG | Chemical synthesis | * * * Shipping We ship worldwide, free delivery above 50£/€/CHF, 5-10 days from dispatch depending on your region. ## Sereniser Supports restful sleep Add to Cart ## Discover the science behind the Sereniser The Sereniser combines clinically studied plant extracts like Safr’Inside™, Holixer™, and Serezin™ with L-theanine, Magnesium Bisglycinate, and Vitamin B6 to support natural sleep rhythms by balancing cortisol, enhancing GABA and serotonin, and restoring deep, uninterrupted rest. Third-party test results See full supplement facts ## Safr’Inside™ 30 mg A standardised, patented, and highly bioavailable saffron extract shown to reduce the time it takes to fall asleep, improve sleep quality, and ease anxious thoughts – by supporting the conversion of serotonin to melatonin and helping balance cortisol levels. ## Holixer™ 250 mg A clinically studied extract from Holy Basil that helps balance cortisol, reduce stress, and activate the parasympathetic nervous system – promoting deeper rest and calmer nights. ## Serezin™ 300 mg A targeted blend of Ginger and Frankincense extracts, designed to support deep, restorative sleep by reducing nighttime discomfort – helping you wake up feeling refreshed and renewed. ## L-Theanine 200 mg A naturally occurring amino acid found in green tea that promotes a calm, focused state without sedation. By supporting alpha brain wave activity, it helps quiet mental overstimulation and eases you into sleep – even after a stressful day. ## Magnesium Bisglycinate 56.25 mg Magnesium is also naturally found in foods like sunflower seeds. We use a highly bioavailable form: magnesium bisglycinate. Bound to glycine, a