Knowledge Base

Last updated: December 1, 2025

Boost your skin and health with Avea's Collagen Activator. Features our patent-pending blend, Colgevity™ for enhanced collagen synthesis, Calcium AKG for ageing reversal, Vitamin C for immune and collagen support, and Astaxanthin as the most powerful antioxidant. A science crafted blend for radiance and fewer wrinkles.

--- url: https://avea-life.com/products/collagen-activator title: Unknown scraped_at: 2025-11-29 type: shopify --- ![Lemon_Collagen_22_Large_c3807f9d-02b6-4d23-9d5d-1ff5fcf7f06b.jpg](https://avea-life.com/cdn/shop/files/Lemon_Collagen_22_Large_c3807f9d-02b6-4d23-9d5d-1ff5fcf7f06b.jpg?crop=center&height=1280&v=1753981955&width=853) 4.8/5 based on over 800 ratings ### Our review platforms Overall **4.8** based on **921** reviews Powered by Top rated on the independent review platform [Trustpilot](https://www.trustpilot.com/review/avea-life.com "https://www.trustpilot.com/review/avea-life.com") ### Collagen Activator Developed in collaboration with longevity scientists at ETH Zurich, the Collagen Activator features **Colgevity™** \- our **patented, 100% vegan collagen precursor** **designed to stimulate natural collagen production**. Unlike most collagen supplements on the market which rely on conventional animal-derived peptides, our formula works upstream to activate the body’s own regenerative processes for deeper, longer-lasting results. Clinically shown to be up to 4x more effective than standard collagen peptides, its synergistic formula: - Stimulates the body's natural collagen production to counteract age-related collagen decline - Enhances skin elasticity and firmness, visibly reducing fine lines and wrinkles - Supports hydration and smoothness for a more radiant, youthful complexion - Strengthens hair and nails with targeted micronutrients essential for keratin structure [SHOP NOW](https://avea-life.com/products/collagen-activator#scroll-to-pdp-div) Stimulates your body’s own collagen production. A patented, 100% vegan formula developed with leading longevity experts in Switzerland, designed to stimulate your body’s own natural collagen production from within. Advanced Collagen StimulationImproved Texture & Firmness Powered by Colgevity™ - our patented, plant-based collagen precursor shown to be up to 4x more effective than generic collagen - this formula stimulates your body’s own collagen production for deeper, longer-lasting results. With Alpha-Ketoglutarate (AKG) and Vitamin C from Acerola Cherry, this synergistic formula supports collagen synthesis and improves skin firmness. Astaxanthin, a powerful antioxidant from microalgae, helps protect against oxidative stress, enhancing skin texture and tone. ![Stimulates your body’s own collagen production.](https://avea-life.com/cdn/shop/files/Collagen_Activator_Pill_E8W.png?v=1753167725&width=800) ## The role of collagen in skin ageing #### Skin Longevity basics Most conversations around skin ageing acknowledge collagen loss, but few explore what it really means, or the solutions available to address it. Collagen is the body’s primary structural protein which forms the scaffolding which gives skin its firmness, elasticity and smooth texture. Unfortunately, from our mid-20s, natural collagen production begins to decline by about 1% each year, accelerating in our 40s, and compounded by external stressors such as UV exposure and oxidative damage. This combination of slowed production and increased breakdown weakens the skin’s internal structure, leading to visible signs of ageing. - Why most collagen supplements are not effective for true collagen synthesis, and what is actually needed Collagen is one of the most vital structural proteins in the body, responsible for keeping skin firm, elastic, and resilient. Yet most collagen supplements fail to deliver meaningful results - not because collagen doesn’t work, but because it only works if it's provided in a form that the body can actually use. Traditional collagen products often rely on hydrolysed animal collagen: large protein fragments that must be broken down and absorbed before they can be used by the body. While these peptides can provide raw materials, their biological impact is limited as the body doesn’t automatically recognise them as a signal to produce more collagen, and in many cases, they are diverted to other functions like general protein metabolism, offering little benefit to the skin. To effectively stimulate collagen renewal, the body needs more than just raw protein. Collagen synthesis is a complex biological process that requires: - **Precise amino acids:** Collagen is primarily built from three key amino acids: glycine, proline, and hydroxyproline. These must be delivered in the right ratio and form to be recognised as collagen-building material. Generic protein or random peptides won’t achieve the same result. - **A biological signal to activate production** Collagen is produced by fibroblasts, which are specialised skin cells that require a biological signal to initiate synthesis. Without this signal, the body has no reason to begin building new collagen, even if the raw materials are present. - **Cofactors that stabilise and support synthesis** Nutrients such as vitamin C and Alpha-Ketoglutarate (AKG) are essential for the enzymatic processes that link collagen fibres and stabilise the matrix. Without them, collagen strands remain weak, disorganised, and prone to breakdown. When these components are missing or imbalanced, the body lacks both the building blocks and the biological instructions needed to produce strong, stable collagen. This is where many supplements fall short - they may supply fragments but fail to engage the skin’s natural regeneration process. - How the Collagen Activator works, and why it’s different from other collagen supplements We developed the Collagen Activator to address a key limitation in the collagen supplement space: most formulas simply deliver fragmented, animal-derived collagen without addressing whether the body can use it. Instead of relying on passive replacement, our formula is designed to actively stimulate the body’s own collagen-building processes. Created in collaboration with longevity researchers and scientists from ETH Zurich, the Collagen Activator features Colgevity™ - our 100% vegan, patented formula clinically shown to be up to 4x more effective than standard collagen supplements¹. It combines a precise ratio of amino acids with targeted co-factors to drive endogenous collagen production - helping to rebuild the structural proteins that keep skin firm, smooth, and elastic. And unlike traditional supplements that use hydrolysed collagen from animal sources, the Collagen Activator works across multiple biological pathways to support natural collagen synthesis at the cellular level: **For replenishing diminishing collagen levels** The foundation of the formula is Colgevity™ - a patented vegan collagen precursor that provides the three key amino acids (glycine, proline, and hydroxyproline) in the precise ratio needed for collagen synthesis. Unlike hydrolysed collagen, which is often broken down before reaching the skin, these building blocks are readily used by fibroblasts to produce new collagen more efficiently, thus helping restore skin volume, structure, and strength. **For boosting skin elasticity & hydration** Acerola cherry extract, a potent natural source of vitamin C, supports collagen cross-linking and protects skin cells from oxidative damage. Together with Alpha-Ketoglutarate (AKG) - a longevity compound that fuels cellular repair - this duo helps improve skin’s elasticity, promote smoother texture, and restore hydration balance at the structural level. **For enhancing skin firmness and reducing fine lines** As collagen production slows, skin begins to lose its firmness and smooth appearance. The Collagen Activator works to restore dermal density by stimulating natural collagen synthesis and reducing inflammation - two critical processes for maintaining tone and preventing the formation of fine lines. The result: visibly firmer, more youthful-looking skin over time. **For strengthening hair and nails** The Collagen Activator provides key amino acids such as Proline, which not only support collagen formation but also contribute to the structure of keratin-rich tissues like hair and nails. Combined with nutrients that enhance tissue repair and integrity, it promotes visibly stronger, less brittle nails and thicker, shinier hair, thus offering a holistic approach to beauty and structural health. - How does the Collagen Activator work with AVEA’s other skin product SkinSpan™? Collagen is essential for maintaining skin firmness, elasticity, and structure, but supporting skin longevity doesn’t stop at collagen production alone. Our Collagen Activator is designed to stimulate collagen synthesis directly at the source using Colgevity™, a patented vegan precursor that delivers the exact amino acids needed to form new collagen. Combined with key cofactors like Acerola Cherry (Vitamin C), Alpha-Ketoglutarate (AKG), and Astaxanthin, it helps reactivate the skin’s natural ability to rebuild its internal scaffolding - thus restoring firmness, improving texture, and strengthening hair and nails over time. [**SkinSpan™**](https://avea-life.com/products/skinspan?srsltid=AfmBOoqshgIB2q2GhDfsFo0orLZb-Lh9A701fb9HA9fxetmJBDblpzoa), on the other hand, addresses _what causes collagen to break down in the first place_. As the skin barrier weakens with age, moisture loss increases, cell renewal slows, and collagen becomes more vulnerable to breakdown. SkinSpan™ reinforces the skin barrier, restores deep hydration, and supports regenerative turnover – creating the ideal conditions for preserving collagen and enhancing the effects of collagen-boosting interventions. Together, these formulas offer a comprehensive approach to skin longevity: - **Collagen Activator** supports collagen production and structural renewal - **SkinSpan™** preserves existing collagen, repairs the skin barrier, and promotes healthy skin regeneration By combining both, you address not just one part of the skin ageing equation, but all of it, thus helping your skin stay firm, smooth, and resilient over time. While improved collagen levels are essential for maintaining skin firmness, elasticity, and structure, preserving existing collagen is just as important as producing more of it. ![](https://avea-life.com/cdn/shop/files/CA_3.0_de1591fe-9754-45a1-88e2-21da8481635a_2000x.png?v=1745034201) clinically backed formula ## Clinical studies on the AVEA® Collagen Activator show: ## 97% noticed improved skin quality in just 30 days⁶ ## 83% experienced better skin hydration in just 30 days⁶ ## 1.4 year reduction in biological age after 6 months measured with TruMe Labs Biological Age test⁶ ## 4x more effective than standard collagen supplements¹ ## Expert-led formulations ### Prof. Collin Ewald Scientist and Professor at ETH Zurich "Collagen molecules are too large to be absorbed directly by the body. With this vegan pre-cursor, Colgevity™, we are telling the body to stimulate its own collagen production for more effective collagen synthesis." ### Dr. med. Intan Pramono Dermatologist, Hautwerk Clinic "Our clinical study found that after a daily intake of the Collagen Activator over a period of 3 months, skin quality significantly improved, measured via Visia Skin Analysis." ### Konstantinos Jiouchas, M.D. Medical Director, Zurich Plastics "AVEA uses a vegan collagen pre-cursor, combined with Vitamin C, AKG and Astaxanthin for more effective results" ### Dr. Cherin Dürr Aesthetic Medicine Expert "For me and my clients, I have noticed a significant improvement in skin health, skin firmness, and skin texture." ### Dr. med. Valentina Bänninger Lead Physician and Co-Founder, Sweet Skin "Collagen is the most important structural protein in our body. As we age, collagen breakdown is more prevalent than collagen renewal. AVEA’s Collagen Activator actively counters this breakdown." Vegan # Collagen Activator 30 sachets per box ![97% report better skin quality within 3 months](https://avea-life.com/cdn/shop/files/Collagen_Activator_Lemon_Lifesytle_1_THIRDMAINIMG_PDP_LANG_EN_HIDE_CLP.png?crop=center&height=2160&v=1747736000&width=2160) ![Collagen Activator Lemon](https://avea-life.com/cdn/shop/files/Collagen_Activator_Lemon_Product_PDP_O8W.png?crop=center&height=4100&v=1747736000&width=4100) ![Collagen Activator Raspberry Mint](https://avea-life.com/cdn/shop/files/CollagenActivatorRaspberrryMint_Product_PDP_O8W.png?crop=center&height=4100&v=1747736000&width=4100) ![Collagen Activator expected benefits](https://avea-life.com/cdn/shop/files/CollagenActivator_Benefits_PDP2.0_LANG_EN.png?crop=center&height=2160&v=1756474274&width=2160) ![Collagen Activator before and after](https://avea-life.com/cdn/shop/files/Collagen_1_Carousel_LANG_EN_1.png?crop=center&height=2160&v=1751461684&width=2160) ![Collagen Activator ingredients](https://avea-life.com/cdn/shop/files/CA_PDP_Ingredients_Carousel_1_LANG_EN.png?crop=center&height=2160&v=1756474274&width=2160) ![Collagen Activator daily intake guide](https://avea-life.com/cdn/shop/files/Daily_Intake_Guide_Collagen_LANG_EN_E8W.png?crop=center&height=1080&v=1756986593&width=1080) ![Collagen Activator supplement facts](https://avea-life.com/cdn/shop/files/Back_of_package_LANG_EN_1.png?crop=center&height=4641&v=1757752162&width=2994) Vegan 4.6/5 (600+ reviews) # Collagen Activator 30 sachets per box $85.00 ~~$0~~Sale _•_ Save Developed in collaboration with longevity scientists at ETH Zurich, the Collagen Activator features Colgevity™ - our next-generation, patented, 100% vegan collagen precursor designed to stimulate your body’s own collagen production. It works across multiple pathways with clinically studied, naturally derived ingredients: - **Colgevity™** delivers the three essential amino acids - glycine, proline, and hydroxyproline - in the precise ratio required to stimulate collagen synthesis at the cellular level. This patented, 100% vegan complex has been shown to be up to 4x more effective than standard collagen peptides. - **Acerola Cherry Extract** provides a potent, highly bioavailable source of natural vitamin C – essential for collagen production – while helping protect against oxidative stress and support skin smoothness. - **Alpha-Ketoglutarate (AKG)** is a longevity-associated molecule that supports cellular energy metabolism and natural collagen formation. It also helps reduce inflammation and promote tissue repair. - **Astaxanthin**, one of the most powerful antioxidants found in nature, is derived from microalgae. It helps protect the skin from UV-induced damage and oxidative stress, which are both major contributors to collagen breakdown and premature ageing. Together, these ingredients work in synergy to stimulate natural collagen production, restore firmness and elasticity – while also supporting stronger hair and nails over time. FlavourLemonRaspberry Mint Subscribe & Save $76.50$2.55 / serving Save up to 25% Annual Save 25% BEST VALUE Quarterly Save 15% MOST POPULAR Monthly Save 10% 1-month supply delivered monthly Pause or cancel at any time One Time Purchase $85.00$2.83 / serving 1 Unit 3 Units Save 5% 6 Units Save 10% MOST POPULAR 12 Units Save 15% BEST VALUE Add to Cart$76.50 90 days money-back guarantee ### FREE Collagen (€79 value) with every order Receive our best-selling, patented Raspberry Mint Collagen Activator for free with every order this Black Friday, only while stocks last. Daily Intake Guide Take one daily Collagen Activator sachet dissolved in a glass of water, smoothie or yoghurt, preferably after a meal or 1–2 hours before bed to promote skin rejuvenation and support restorative sleep thanks to its Glycine content. * * * Supplement Facts ![](https://avea-life.com/cdn/shop/files/WINNER_SEAL_BSA_-_PNG_transparent_background.png?v=1750702756&width=80)![](https://avea-life.com/cdn/shop/files/Wellness_and_longevity_choice_award_2025.png?v=1750754025&width=80)![](https://avea-life.com/cdn/shop/files/Vegan_Beauty_WINNER.png?v=1750753860&width=80) ![](https://avea-life.com/cdn/shop/files/iconography_E8W_swiss_made.svg?v=1750241596&width=20)Manufactured in Switzerland ![](https://avea-life.com/cdn/shop/files/iconography_E8W_expert_formulated.svg?v=1750239541&width=20)Formulated by Experts ![](https://avea-life.com/cdn/shop/files/package_2_24dp_3C7289_FILL0_wght100_GRAD0_opsz24_1.svg?v=1750239788&width=20)Sustainable Packaging ![](https://avea-life.com/cdn/shop/files/iconography_E8W_clinically_proven.svg?v=1750239926&width=20)Clinically proven results ![](https://avea-life.com/cdn/shop/files/iconography_E8W_vegan.svg?v=1750241688&width=20)Vegan ![](https://avea-life.com/cdn/shop/files/Halal.svg?v=1750239967&width=20)Halal Active ingredients: Colgevity™ 8,400 mg (L-glycine 5,000 mg, L-hydroxyproline 1,700 mg, L-proline 1,700 mg), Calcium Alpha-ketoglutarate 1,000 mg, Algae Powder 200 mg (as Astaxanthin 4 mg), Acerola fruit juice extract 150 mg (provides vitamin C 48 mg) Other ingredients: - Silicon dioxide as anti-caking agent to ensure the powder’s free-flowing nature, improve manufacturing processes, maintain ingredient uniformity and enhance the stability of the final product - Citric acid as acidity regulator to stabilize pH, enhance flavor, improve solubility, prevent microbial growth and protect the product’s active ingredients, ensuring a high-quality and enjoyable final product - Steviol glycosides from stevia as sweetener to serve as a natural, calorie-free sweetener that enhances the taste, masks unpleasant flavors and improves the palatability of drinks while being suitable for various dietary preferences and restrictions - Natural raspberry flavours as flavour to enhance taste, mask unpleasant notes, improve consumer appeal and encourage regular consumption of the product (included only in Collagen Activator Lemon Raspberry) - Peppermint oil powder as flavour to improve taste, mask undesirable flavors, provide a refreshing cooling effect and enhance the sensory experience (included only in Collagen Activator Lemon Raspberry) - Safflower concentrate (carthamus) as colouring food to enhance visual appeal, standardize product appearance and align with consumer preferences for clean-label, plant-based ingredients (included only in Collagen Activator Lemon) - Natural lemon flavour as flavour to enhance taste, mask unpleasant notes, improve consumer appeal and encourage regular consumption of the product (included only in Collagen Activator Lemon) * * * Benefit references Our formulations are based on cutting-edge Longevity research. Led by Chief Science Officer Sophie Chabloz, our team collaborates with longevity experts from top institutions to create highly effective, science-backed products. | Ingredients | Benefits | | --- | --- | | Supports healthy collagen production | Promotes healthy skin elasticity and hydration | Supports the skin’s natural resilience to environmental stressors | Promotes the body’s natural antioxidant processes | Supports healthy joint function | Promotes physical vitality during aging | Supports healthy mitochondrial function and energy production | Promotes vitality and healthy aging processes | | --- | --- | --- | --- | --- | --- | --- | --- | | L-Glycine / L-Proline / L-Hydroxyproline | [Karna et al., 2020](https://pmc.ncbi.nlm.nih.gov/articles/PMC7228914/)<br>[Chen et al., 2023](https://pubmed.ncbi.nlm.nih.gov/37970760/) | [Al-Atif, 2022](https://pmc.ncbi.nlm.nih.gov/articles/PMC8824545/)<br>[Proksh et al., 2013](https://pubmed.ncbi.nlm.nih.gov/23949208/) | | [Ruiz-Ramirez et al., 2014](https://pubmed.ncbi.nlm.nih.gov/23742196/) | [Clark et al., 2008](https://pubmed.ncbi.nlm.nih.gov/18416885/)<br>[Bello and Oesser, 2006](https://www.tandfonline.com/doi/abs/10.1185/030079906X148373)<br>[Moskowitz, 2000](https://www.sciencedirect.com/science/article/abs/pii/S0049017200568255)<br>[Benito-Ruiz et al., 2009](https://www.tandfonline.com/doi/abs/10.1080/09637480802498820) | [Haus et al., 2007](https://pubmed.ncbi.nlm.nih.gov/17901242/)<br>[Bisset and Howlett, 2022](https://www.mdpi.com/2072-6643/14/14/2806)<br>[Rene et al., 2017](https://journals.lww.com/co-clinicalnutrition/Abstract/2017/07000/Glycine_metabolism_in_skeletal_muscle_.2.aspx) | [Bannai et al., 2012](https://pubmed.ncbi.nlm.nih.gov/22529837/) | [Brind et al., 2011](https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fasebj.25.1_supplement.528.2) | | Alpha-Ketoglutarate | [Son et al., 2007](https://pubmed.ncbi.nlm.nih.gov/17666792/) | | [Son et al., 2007](https://pubmed.ncbi.nlm.nih.gov/17666792/) | [Shahmirzadi et al., 2020](https://www.sciencedirect.com/science/article/pii/S1550413120304174)<br>[He et al., 2017](https://pmc.ncbi.nlm.nih.gov/articles/PMC5732704/)<br>[He et al., 2018](https://pubs.acs.org/doi/abs/10.1021/acs.jafc.8b04470) | [Filip et al., 2007](https://pubmed.ncbi.nlm.nih.gov/17896582/) | [Shahmirzadi et al., 2020](https://www.sciencedirect.com/science/article/pii/S1550413120304174)<br>[Chin et al., 2014](https://www.nature.com/articles/nature13264)<br>[Rhoads and Anderson, 2020](https://www.sciencedirect.com/science/article/pii/S1550413120304228)<br>[Bisset and Howlett, 2022](https://www.mdpi.com/2072-6643/14/14/2806)<br>[Wang et al., 2020](https://www.nature.com/articles/s41467-020-19360-1) | [Zdzisinska et al., 2016](https://pubmed.ncbi.nlm.nih.gov/27326424/)<br>[Bayliak and Lushchak, 2020](https://pubmed.ncbi.nlm.nih.gov/33340716/)<br>[Shahmirzadi et al., 2020](https://www.sciencedirect.com/science/article/pii/S1550413120304174)<br>[Chin et al., 2014](https://www.nature.com/articles/nature13264) | [Shahmirzadi et al., 2020](https://www.sciencedirect.com/science/article/pii/S1550413120304174)<br>[Chin et al., 2014](https://www.nature.com/articles/nature13264)<br>[Demidenko et al., 2021](https://pubmed.ncbi.nlm.nih.gov/34847066/) | | Astaxanthin | [Chou et al., 2020](https://www.semanticscholar.org/paper/Purified-Astaxanthin-from-Haematococcus-pluvialis-Chou-Ma/40e74b3181fe5651b71a05eac7ef3ecc2e41853f) | [Manzanaris et al., 2021](https://athenaeumpub.com/wp-content/uploads/Synergistic-antiaging-and-Dermal-Restorative-Effects-of-an-Oral-Bioactive-Procollagen-and-Astaxanthin-Supplement.pdf)<br>[Tominaga et al., 2017](https://pmc