Knowledge Base

--- url: https://avea-life.com/pages/cell-primer-science title: Unknown scraped_at: 2025-11-29 type: shopify --- Cell Primer Science Cell Primer is formulated with powerful compounds such as Fisetin, Quercetin, and Spermidine. It is meticulously crafted to boost autophagy, clear senescent cells, and set the foundation for peak cellular health and rejuvenation. Priming your cells for greatness ## Taking cellular health to a whole new level  Science-backed compounds ## 6 well-researched active ingredients ## Quercetin  A powerful antioxidant and senolytic found in fruits and vegetables such as red onions, exhibiting anti-inflammatory properties and supporting overall health. ## Fisetin  A naturally occurring senolytic compound found in strawberries, holds the potential to combat senescent or 'zombie cells' accumulation in our bodies. ## PQQ  A coenzyme and antioxidant supporting cellular energy production. It is naturally found in the body but tends to decline with age. Also found in trace amounts in fermented soybeans and green peppers. ## Ergothioneine  Found in mushrooms, this natural antioxidant is known for its exceptional cellular protection attributes. By shielding our cells from oxidative stress, it aids in maintaining their health and vitality. ## Spermidine  A natural polyamine and famous longevity ingredient found in wheat germ and soybeans, renowned for its ability to stimulate autophagy, the vital process of cellular self-renewal. ## Selenium  An essential trace mineral found in nuts and seafood, supporting immune function, antioxidant defence against cell damage, reproduction and energy production.  Like a cleanse for your cells ## Supporting autophagy for a clean slate Autophagy is a natural process where cells break down and recycle their own damaged components, essentially a cellular "cleanup" mechanism. It keeps cells healthy by removing harmful debris and making way for new cell growth. Spermidine supports autophagy through various mechanisms, such as inhibiting specific proteins, regulating signalling pathways, and promoting metabolic changes.  Getting rid of Zombie Cells ## Activating senescent cell clearance As you age, your body accumulates "worn-out" cells that no longer function properly. Accumulation of these senescent cells, over time, leads to chronic inflammation, a well-recognised marker for many age-related diseases. Natural senolytics like Quercetin and Fisetin have great potential in clearing out senescent cells, as shown in clinical studies. [Try Our Cell Primer](https://avea-life.com/products/cell-primer)  Up your antioxidant supply ## Protecting cells against oxidative damage Oxidative stress occurs when there's an imbalance between free radicals and antioxidants in the body, leading to cell damage and ageing. The Cell Primer contains potent antioxidants like Ergothioneine, Quercetin, PQQ and Selenium. They support energy production in your cells, and even help repair and rejuvenate cells by neutralising damaging free radicals. [Try Our Cell Primer](https://avea-life.com/products/cell-primer) SCIENTIFIC EVIDENCE ## Revolutionising cellular health | Benefits | References | | --- | --- | | Promotes autophagy | Hofer et al., [2022](https://pubmed.ncbi.nlm.nih.gov/37118547/ "https://pubmed.ncbi.nlm.nih.gov/37118547/")<br>Zhang et al., [2020](https://pubmed.ncbi.nlm.nih.gov/32184730/ih.gov/20427238/ "https://pubmed.ncbi.nlm.nih.gov/32184730/")<br>Park et al., [2019](https://pubmed.ncbi.nlm.nih.gov/30662534/ "https://pubmed.ncbi.nlm.nih.gov/30662534/")<br>Jia et al., [2019](https://pubmed.ncbi.nlm.nih.gov/26884726/ "https://pubmed.ncbi.nlm.nih.gov/26884726/")<br>Kim et al., [2016](https://pubmed.ncbi.nlm.nih.gov/27112200/ "https://pubmed.ncbi.nlm.nih.gov/27112200/")<br>Klimaszewska-Wisniewska et al., [2016](https://pubmed.ncbi.nlm.nih.gov/26884726/ "https://pubmed.ncbi.nlm.nih.gov/26884726/")<br>Minois, [2014](https://pubmed.ncbi.nlm.nih.gov/24481223/ "https://pubmed.ncbi.nlm.nih.gov/24481223/")<br>Eisenberg et al., [2009](https://pubmed.ncbi.nlm.nih.gov/19801973/ "https://pubmed.ncbi.nlm.nih.gov/19801973/") | | Mitigates senescent cells | Huard et al., [2023](https://pubmed.ncbi.nlm.nih.gov/37627641/ "https://pubmed.ncbi.nlm.nih.gov/37627641/")<br>Apparoo et al., [2022](https://pubmed.ncbi.nlm.nih.gov/36244584/ "https://pubmed.ncbi.nlm.nih.gov/36244584/")<br>Kirkland et al., [2020](https://pubmed.ncbi.nlm.nih.gov/32686219/ "https://pubmed.ncbi.nlm.nih.gov/32686219/")<br>Baek et al., [2020](https://pubmed.ncbi.nlm.nih.gov/33318630/ "https://pubmed.ncbi.nlm.nih.gov/33318630/")<br>Yousefzade et al., [2018](https://pubmed.ncbi.nlm.nih.gov/30279143/ "https://pubmed.ncbi.nlm.nih.gov/30279143/")<br>Zhu et al., [2017](https://pubmed.ncbi.nlm.nih.gov/28273655/ "https://pubmed.ncbi.nlm.nih.gov/28273655/")<br>D' Onofrio et al., [2016](https://pubmed.ncbi.nlm.nih.gov/27101740/ "https://pubmed.ncbi.nlm.nih.gov/27101740/")<br>Zhu et al., [2015](https://pubmed.ncbi.nlm.nih.gov/31614433/https://pubmed.ncbi.nlm.nih.gov/25754370/ "https://pubmed.ncbi.nlm.nih.gov/25754370/") | | Supports cellular health | Aghababaei et al., [2023](https://pubmed.ncbi.nlm.nih.gov/37513932/ "https://pubmed.ncbi.nlm.nih.gov/37513932/")<br>Ni et al., [2021](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612618/ "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8612618/")<br>Xia et al., [2021](https://pubmed.ncbi.nlm.nih.gov/33443499/ "https://pubmed.ncbi.nlm.nih.gov/33443499/")<br>Wang et al., [2017](https://pubmed.ncbi.nlm.nih.gov/29441149/ "https://pubmed.ncbi.nlm.nih.gov/29441149/")<br>Zhang et al., [2012](https://pubmed.ncbi.nlm.nih.gov/22040225/ "https://pubmed.ncbi.nlm.nih.gov/22040225/") | | Enhanced anti-inflammatory properties | Mahmoodpoor et al., [2023](https://pubmed.ncbi.nlm.nih.gov/36405547/ "https://pubmed.ncbi.nlm.nih.gov/36405547/")<br>Deepika et al., [2022](https://pubmed.ncbi.nlm.nih.gov/35458696/ "https://pubmed.ncbi.nlm.nih.gov/35458696/")<br>Borodina et al., [2020](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653990/ "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653990/")<br>Choi et al., [2012](https://pubmed.ncbi.nlm.nih.gov/22433014/ "https://pubmed.ncbi.nlm.nih.gov/22433014/")<br>Laurenza et al., [2008](https://pubmed.ncbi.nlm.nih.gov/19509460/ "https://pubmed.ncbi.nlm.nih.gov/19509460/")<br>Rahman et al., [2003](https://pubmed.ncbi.nlm.nih.gov/12646250/ "https://pubmed.ncbi.nlm.nih.gov/12646250/") | Ingredient safety profile | Ingredients | References | | --- | --- | | Quercefit (Quercetin) | [Mirza M.A., et al., 2023](https://www.mdpi.com/1424-8247/16/11/1631)<br>[Andres S., et al., 2017](https://onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.201700447) | | Wheat Germ Extract Spermidine | [Heimbach J.T., et al., 2017](https://journals.sagepub.com/doi/10.1080/10915810701369709)<br>[Hofer S.J., et al., 2022](https://www.nature.com/articles/s43587-022-00322-9) | | Fisetin Extract | [Hassan S.S., et al., 2022](https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.1015835/full)<br>[Luca & Trifan, 2023](https://link.springer.com/referenceworkentry/10.1007/978-3-030-94753-8_23-1) | | PQQ (Pyrroloquinoline Quinone) | [European Food Safety Authority](https://www.efsa.europa.eu/en/efsajournal/pub/5058)<br>[fda.gov](http://fda.gov/) | | L-Ergothioneine | [European Food Safety Authority](https://www.efsa.europa.eu/en/efsajournal/pub/4629) | | Selenium** (as L-Selenomethionine) | [European Food Safety Authority](https://www.efsa.europa.eu/en/efsajournal/pub/7704)