10 science-proven benefits of Lactobacillus casei supplements for boosting longevity - AVEA Life Insights

--- url: https://insights.avea-life.com/gut-health/lactobacillus-casei-supplements/ title: 10 science-proven benefits of Lactobacillus casei supplements for boosting longevity - AVEA Life Insights scraped_at: 2025-11-30 type: wordpress --- # 10 science-proven benefits of Lactobacillus casei supplements for boosting longevity Written by [Aishani Rajarai](https://insights.avea-life.com/author/aishani-rajarai/) Whether it’s cracking the code to optimal health or simply maintaining balance in a hectic world, one thing is certain—your gut plays a damn crucial role. _Lactobacillus casei_, recently reclassified as _Lacticaseibacillus casei_, is the probiotic powerhouse you may not have heard of, but definitely need on your radar. [Probiotics](http://insights.avea-life.com/gut-health/nutrition/probiotics-vs-prebiotics/) have been the centre of attention lately, but _Lacticaseibacillus casei_ stands apart, backed by years of scientific research. **_Lactobacillus casei._** This versatile bacterium is celebrated for its far-reaching benefits, from strengthening your immune system and improving digestion, to supporting liver function and even enhancing metabolic health. It’s earned its reputation as a key player in longevity, featured both in cutting-edge supplements and traditional fermented foods. In this Avea article, we’ll delve into the science behind _Lacticaseibacillus casei_, explore how it can support your health, and discuss the best ways to incorporate it into your daily routine. Let’s have a closer look at how this remarkable probiotic can contribute to your well-being and longevity. For simplicity, we will still use the term _Lactobacillus casei_, or _L. Casei_. ## What Is _Lactobacillus Case_ i? _Lactobacillus casei_ is a gram-positive, rod-shaped bacterium that belongs to the _Lactobacillus_ genus. This family of bacteria is renowned for its role in fermentation, which is why _L. casei_ is found in many dairy products, including cheese and yoghurt. It also naturally resides in the human digestive and reproductive tracts. The probiotic properties of _L. casei_ make it a powerhouse for gut health. As a non-motile and non-sporulating organism, it ferments sugars into lactic acid, helping to regulate the pH of its surroundings. For this reason, L. casei is widely used commercially in the fermentation process of dairy products. What sets _L. casei_ apart from other _Lactobacilli_ is its ability to thrive across a range of pH levels and temperatures. This adaptability means it can survive the journey through the digestive tract and make its way to where it’s needed. Extensive research on _Lactobacillus casei_ has highlighted several health benefits, including: - Enhancing immune response. - Improving digestion and supporting gut health. - Alleviating liver inflammation. - Modulating metabolism. - Boosting antioxidant defences. * * * ### 1\. Gram-positive bacterium _Lactobacillus casei_ is a gram-positive bacterium, meaning it has a thick cell wall that retains the violet stain used in Gram staining—a key method for bacterial classification. This structure offers protection from environmental stressors, allowing _L. casei_ to thrive even in the acidic environment of the stomach. This resilience ensures it reaches the intestines intact, where it can exert its probiotic effects. * * * ### 2\. Facultatively anaerobic bacterium Unlike some bacteria, _Lactobacillus casei_ is facultatively anaerobic, meaning it can survive in both oxygen-rich and oxygen-poor environments. This adaptability is crucial for its survival in the human gut, where oxygen levels vary. In the gut, _L. casei_ ferments carbohydrates, producing lactic acid. This fermentation process helps lower the pH of the gut, which inhibits harmful pathogens and promotes a healthy microbial balance. * * * ### 3\. Non-motile bacterium _Lactobacillus casei_ is also non-motile, meaning it lacks the ability to move independently. Whilst this might seem like a limitation, it is actually advantageous for stability. Rather than moving around, _L. casei_ adheres to the gut lining, where it can colonise effectively. By establishing itself in the intestines, it helps maintain a balanced gut environment, supporting digestion, immune function, and protecting against the overgrowth of harmful bacteria. ## Is _Lactobacillus Casei_ a probiotic? Yes! _Lactobacillus casei_ is a well-known probiotic, meaning it’s a type of bacteria that’s good for you, especially when it comes to digestion and immunity. Probiotics like _Lactobacillus casei_ are essential for maintaining a healthy balance in your gut microbiota–the collection of bacteria living in your digestive system. A healthy gut means better digestion, a stronger immune system, and even improved mental health. Learn [why your gut microbiome matters with Dr Will Bulsiewicz](http://insights.avea-life.com/gut-health/nutrition/gut-doctor/), the gut doctor. ## Is _Lactobacillus Paracasei_ the same as _Lactobacillus Casei_? Although these two bacteria are from the same family, they are not the same. _Lactobacillus paracasei_ and _Lactobacillus casei_ have different strains and benefits. Both are probiotics, but they have unique characteristics that help in different ways. Whilst _Lactobacillus paracasei_ is mainly studied for its immune-boosting properties, _Lactobacillus casei_ has a broader impact, helping in digestion, immune function, and even liver health. ## What does _Lactobacillus Casei_ do for your health? So, what can this tiny bacterium do for you? As it turns out, a lot! Let’s break down its key benefits and how they can make a difference in your life. ### 1\. Supporting your immune system and fighting respiratory infections When it comes to protecting your body from illness, your immune system is your first line of defence–and _Lactobacillus casei_ can give it a serious boost. Studies on mice have shown that _L. casei_ helps the immune system recover faster after infections like _Streptococcus pneumoniae_, a common respiratory pathogen. In human studies, _L. casei 431_ reduced the duration of common cold symptoms, though it didn’t significantly impact the body’s response to flu vaccines. If you’re someone who struggles with frequent colds or respiratory infections, adding _L. casei_ to your daily routine could help reduce the severity and duration of those pesky illnesses. ### 2\. Improving your gut health and digestive balance We often think about digestion when talking about probiotics, and _L. casei_ is no exception. By balancing the bacteria in your gut, _L. casei_ can help prevent issues like diarrhoea and constipation. In preterm infants, combining _L. casei_ with other probiotics like [_Bifidobacterium breve_](http://insights.avea-life.com/gut-health/supplements/bifidobacterium-breve-supplement/) has been shown to reduce the risk of necrotising enterocolitis (NEC), a dangerous intestinal condition. For adults, _L. casei_ can be just as beneficial. It has been shown to maintain gut integrity, reducing the risk of diarrhoea, constipation, and other digestive imbalances by inhibiting harmful bacteria. Whether you’re dealing with occasional digestive discomfort or looking to strengthen your gut’s natural defences, _L. casei_ offers reliable support. ### 3\. Enhancing your liver health and reducing inflammation Whilst probiotics are often associated with gut health, _Lactobacillus casei_ offers benefits beyond the digestive system. Research in animal models has shown that this probiotic helps protect the liver by reducing inflammation. In particular, _L. casei_ was found to lower levels of pro-inflammatory cytokines, which play a role in liver damage, and increase antioxidant activity, helping the liver detoxify more effectively. Although more human studies are needed, the existing evidence suggests that _L. casei_ may be a useful supplement for those concerned about liver health, especially in the context of inflammation and oxidative stress. Adding it to your routine could help promote liver function and reduce the risk of liver-related issues over time. ### 4\. Boosting antioxidant defences and protecting from free radicals [Oxidative stress](http://insights.avea-life.com/healthy-ageing/tips/oxidative-stress/) is something many of us face daily, whether from environmental toxins, poor diet, or simply stress itself. The good news? _Lactobacillus casei_ has been shown to boost your body’s antioxidant defences. Studies have found that when combined with prebiotics like inulin, _L. casei_ can increase antioxidant enzyme activity, helping neutralise harmful free radicals that damage cells and contribute to chronic diseases. For those seeking to reduce the effects of oxidative stress, whether to slow down the ageing process or lower the risk of conditions like heart disease and cancer, _L. casei_ offers a natural way to boost your body’s defences and promote cellular health. Learn more about the importance of antioxidants for anti-ageing [here](http://insights.avea-life.com/healthy-ageing/nutrition/antioxidants-for-longevity/). ## Experience Avea’s next-gen probiotic supplement  - 4x probiotic survival: **Advanced Duocap® technology** - **Targeted gut-brain support**: Panax Ginseng, 10 strains, including, _Lacticaseibacillus casei,_ Vitamin B6 & B12 - Backed by science: **1000+ studies** [LEARN MORE](https://avea-life.com/products/biomind/) [Avea’s Biomind](https://avea-life.com/products/biomind) ### 5\. Promoting a healthy lipid profile for your heart health Concerned about your cholesterol levels? _Lactobacillus casei_ may have something to offer. Research has shown that fermented milk products containing _L. casei_ can help improve your lipid profile. In studies on obese adults, _L. casei_ was linked to reductions in total cholesterol, LDL (bad cholesterol), and triglyceride levels, whilst preserving HDL (good cholesterol). This effect on lipid levels suggests that _L. casei_ may play a role in supporting cardiovascular health, making it a valuable addition to a heart-healthy diet and lifestyle. By improving cholesterol balance, this probiotic could help reduce the risk of cardiovascular issues in the long term. ### 6\. Promoting healthy weight Obesity is a complex condition influenced by genetics, lifestyle, and gut health. _Lactobacillus casei_ has shown promise in studies aimed at managing weight and improving metabolic health. In animal models, _L. casei_ was linked to improvements in gut microbiota composition and reductions in obesity markers. In human studies, fermented milk containing _L. casei_ helped improve the gut microbiota in obese individuals, potentially aiding in weight management. There’s even evidence to suggest that _L. casei_ could help manage weight in certain populations by influencing gut hormones and reducing inflammation, making it a useful addition to a weight management plan. ### 7\. Alleviating allergy symptoms and inflammation If allergies are making your life difficult, _Lactobacillus casei_ might help. Studies have found that specific strains of _L. casei_ can modulate the immune response, reducing inflammation and helping the body manage allergic reactions more effectively. In both animal and human studies, synbiotic combinations featuring _L. casei_ were shown to alleviate atopic dermatitis and other allergy-related symptoms, offering a natural alternative to managing inflammatory responses. The rise in childhood asthma and allergies has been linked to a decrease in early-life exposure to microbes, and probiotics may help counter this by supporting a healthy balance of gut bacteria. Research has shown that children who had early exposure to _L. casei_ and other probiotic strains were less likely to develop allergies by the age of five. By supporting the immune system and promoting a balanced inflammatory response, _L. casei_ can help improve your body’s tolerance to allergens and potentially reduce the frequency or severity of allergic reactions. ### 8\. Enhancing oral health Taking _Lactobacillus casei_ has been shown to help reduce harmful bacteria that live in the spaces between your teeth and gums, known as subgingival plaque. These bacteria are a major cause of gum disease, which can lead to inflammation, bleeding gums, and even tooth loss if left untreated. By lowering the levels of these harmful bacteria, _L. casei_ can help improve your gum health and reduce the risk of periodontal (gum) disease. Essentially, it acts as a natural helper for keeping your mouth and gums healthier over time. Remember, oral health is not about a bright smile–it’s deeply connected to the state of your overall health and longevity. ### 9\. Supporting your mental health and brain function It’s no longer a surprise to see how probiotics can help with mental health and cognitive function. Research into the gut-brain axis, the connection between your gut and brain, suggests that probiotics like _L. casei_ can influence mood and brain function. In animal studies, strains from the _L. casei_ group have been shown to reduce anxiety and depressive behaviour by altering the brain’s response to stress. The effect of probiotics on mental health is so promising that the term “psychobiotics” has been coined to describe bacteria that can positively influence mental well-being. By helping to regulate the gut microbiota, _L. casei_ may offer support for mental health, potentially improving mood and cognitive function. ### 10\. Potential role in cancer prevention Emerging research suggests that _Lactobacillus casei_ might play a role in cancer prevention. In animal studies, _L. casei_ has been linked to a reduction in tumour size and cancer cell viability. Specifically, in a study on colon cancer, _L. casei_ was shown to reduce tumour volume by up to 80%, likely by attaching to cancer cells and triggering their death. Whilst these findings are still in the early stages and more research is needed, the results are promising. Probiotics like _L. casei_ may offer potential in the future as part of cancer prevention or adjunctive treatments, particularly in colon and colorectal cancer. ## Is _Lactobacillus casei_ safe to use? _Lactobacillus_ is a large group of bacteria, with over 200 species, naturally found in the human digestive and urogenital tracts. They are also present in many foods like yoghurt, sauerkraut, and fermented products. These bacteria have been used in food fermentation for centuries, leading to their recognition as safe by the US Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA). The _Lactobacillus casei_ group (LCG), which includes _L. casei_, _L. paracasei_, and _L. rhamnosus_, is well-studied for its health benefits. When taken as a supplement, _L. casei_ is safe and generally well-tolerated, even with long-term use. Some people may experience temporary bloating or gas as their gut adjusts to the introduction of beneficial bacteria. These mild symptoms usually subside as the microbiome stabilises, allowing you to enjoy the long-term benefits of improved digestion and overall gut health. ## Where can you find _Lactobacillus Casei_? ### 1\. Foods that contain _Lactobacillus Casei_ Luckily, getting more _Lactobacillus casei_ in your diet doesn’t have to be complicated. Here are some foods rich in this powerful probiotic: - **Yoghurt**: Many probiotic yoghurts contain _L. casei_, making it a simple, tasty way to improve your gut health. Look for yoghurts that specifically mention probiotics or live cultures on the label. - **Cheese**: Some types of fermented cheese, like Gouda, are great sources of _L. casei_. A small amount can go a long way in supporting your gut microbiota. - **Fermented vegetables**: Sauerkraut and kimchi are both packed with beneficial probiotics, including _L. casei_. These tangy vegetables make a delicious addition to meals while also helping your digestive system. Discover the benefits of [fermented foods for longevity](http://insights.avea-life.com/gut-health/nutrition/fermented-foods/). ### 2\. Probiotic supplements with _Lactobacillus casei_ _Lactobacillus casei_ is frequently included in probiotic supplements that are designed to support gut health and overall well-being. This versatile bacterium is often combined with other probiotic strains to maximise its digestive and immune-boosting benefits. #### Avea’s Biomind At Avea, we’ve created [**Biomind**](https://avea-life.com/products/biomind/), a comprehensive probiotic supplement that focuses on gut health, mental well-being, and brain function, incorporating our proprietary strain of _Lactobacillus casei,_ carefully chosen for its proven benefits. [](https://avea-life.com/products/biomind/) [LEARN MORE](https://avea-life.com/products/biomind/) #### Why you should try Biomind [**Biomind**](https://avea-life.com/products/biomind/) is a next generation supplement, backed by 1000+ studies on its blend of ingredients. Each dose contains 30 billion CFUs (colony-forming units) from 10 well-researched strains, including _Lactobacillus casei_ (2 billion CFUs). Our potent formula is designed to promote digestive balance, strengthen your immune system, and enhance mental clarity by supporting your gut-brain axis. [LEARN MORE](https://avea-life.com/products/biomind/) Our _Lactobacillus casei_ strain is carefully selected through a partnership with Nordic Biotic, a Danish leader in probiotic research. Through their rigorous in vitro and clinical studies, our strain has been proven to potentially - help with symptoms of IBS and may relieve chronic constipation. - support the digestion of lactose, easing symptoms of lactose intolerance. - reduce inflammation, which may improve mood and support mental health through its role in gut health. - strengthen the immune system and shorten the duration of common colds and other respiratory infections. _Lactobacillus casei_ works alongside other strains in [**Biomind**](https://avea-life.com/products/biomind/) to help restore balance to the gut microbiota. In fact, when combined with other strains like _Bifidobacterium bifidum_(as present in Biomind), it strengthens the immune response, supporting nutrient absorption and overall vitality. #### Advanced delivery system for maximum effectiveness Another reason you should consider Avea’s [**Biomind**](https://avea-life.com/products/biomind/) is for its innovative Duocap® technology—a capsule-in-capsule delivery system that ensures slow, targeted release of the probiotics and nutrients. This advanced delivery method allows _Lactobacillus casei_ and other strains to reach their ideal location in your digestive tract, enhancing nutrient absorption, reducing gut inflammation, and reinforcing the gut-brain connection for a holistic approach to health and wellness. [TRY NOW](https://avea-life.com/products/biomind/) ## Keynote from Avea - _Lacticaseibacillus casei_ is a versatile probiotic with proven benefits for gut health, immunity, liver function, and even mental well-being. - It can be found in [fermented foods](http://insights.avea-life.com/gut-health/nutrition/fermented-foods/) like yoghurt, cheese, and sauerkraut, as well as in [probiotic supplements](https://avea-life.com/products/biomind/) designed to support digestive and immune function. - _L. casei_ is safe for long-term use, though some people may experience mild digestive symptoms like bloating as their gut adjusts. - Emerging research highlights the potential of _L. casei_ in boosting brain health, managing weight, and supporting oral, heart, and liver health. Dive deeper into the scientific paper on _L.Casei_ [here](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6160870/). By [Aishani Rajarai](https://insights.avea-life.com/author/aishani-rajarai/) Aishani Rajarai is a scientific writer and neuroscience enthusiast. She holds a BSc in biochemistry and cell biology, and a minor in medicinal chemistry and chemical biology. Her mission at Avea is to bring the science of longevity through blog posts, newsletters, podcasts, and social media content to the public, so people can live a healthier, longer, and happier life. [](https://avea-life.com/products/biomind) ### Biomind [Learn More](https://avea-life.com/products/biomind) Supports digestive health and mental well-being €49.0 Biomind - €49.0  add to cart