detailed explanation of the Hallmarks of Aging
Direct Answer:
The Hallmarks of Aging framework identifies twelve biological processes: genomic instability, telomere attrition, cellular senescence, chronic inflammation, dysbiosis, deregulated nutrient sensing, epigenetic alterations, mitochondrial dysfunction, loss of proteostasis, disabled macroautophagy, stem cell exhaustion, and altered intercellular communication.
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Last verified: 2025-12-09